Search references:
| 1. | Gruber, Christoph G; Frey, Laura; Guntermann, Roman; Medina, Dana D; Cortés, Emiliano: Early stages of covalent organic framework formation imaged in operando. In: Nature, 630 (8018), pp. 872 – 877, 2024, ISSN: 00280836, (Cited by: 1; All Open Access, Hybrid Gold Open Access). (Type: Journal Article | Abstract | Links | BibTeX) @article{Gruber2024872, title = {Early stages of covalent organic framework formation imaged in operando}, author = {Christoph G Gruber and Laura Frey and Roman Guntermann and Dana D Medina and Emiliano Cortés}, url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85195313423&doi=10.1038%2fs41586-024-07483-0&partnerID=40&md5=1f3ff910ff4628e063fe30f3abd6cb8e}, doi = {10.1038/s41586-024-07483-0}, issn = {00280836}, year = {2024}, date = {2024-01-01}, journal = {Nature}, volume = {630}, number = {8018}, pages = {872 – 877}, publisher = {Nature Research}, abstract = {Covalent organic frameworks (COFs) are a functional material class able to harness, convert and store energy. However, after almost 20 years of research, there are no coherent prediction rules for their synthesis conditions. This is partly because of an incomplete picture of nucleation and growth at the early stages of formation. Here we use the optical technique interferometric scattering microscopy (iSCAT)1–3 for in operando studies of COF polymerization and framework formation. We observe liquid–liquid phase separation, pointing to the existence of structured solvents in the form of surfactant-free (micro)emulsions in conventional COF synthesis. Our findings show that the role of solvents extends beyond solubility to being kinetic modulators by compartmentation of reactants and catalyst. Taking advantage of these observations, we develop a synthesis protocol for COFs using room temperature instead of elevated temperatures. This work connects framework synthesis with liquid phase diagrams and thereby enables an active design of the reaction environment, emphasizing that visualization of chemical reactions by means of light-scattering-based techniques can be a powerful approach for advancing rational materials synthesis. © The Author(s) 2024.}, note = {Cited by: 1; All Open Access, Hybrid Gold Open Access}, keywords = {}, pubstate = {published}, tppubtype = {article} } Covalent organic frameworks (COFs) are a functional material class able to harness, convert and store energy. However, after almost 20 years of research, there are no coherent prediction rules for their synthesis conditions. This is partly because of an incomplete picture of nucleation and growth at the early stages of formation. Here we use the optical technique interferometric scattering microscopy (iSCAT)1–3 for in operando studies of COF polymerization and framework formation. We observe liquid–liquid phase separation, pointing to the existence of structured solvents in the form of surfactant-free (micro)emulsions in conventional COF synthesis. Our findings show that the role of solvents extends beyond solubility to being kinetic modulators by compartmentation of reactants and catalyst. Taking advantage of these observations, we develop a synthesis protocol for COFs using room temperature instead of elevated temperatures. This work connects framework synthesis with liquid phase diagrams and thereby enables an active design of the reaction environment, emphasizing that visualization of chemical reactions by means of light-scattering-based techniques can be a powerful approach for advancing rational materials synthesis. © The Author(s) 2024. |
References (last update: Sept. 23, 2024):
2024 |
Gruber, Christoph G; Frey, Laura; Guntermann, Roman; Medina, Dana D; Cortés, Emiliano Early stages of covalent organic framework formation imaged in operando Journal Article Nature, 630 (8018), pp. 872 – 877, 2024, ISSN: 00280836, (Cited by: 1; All Open Access, Hybrid Gold Open Access). Abstract | Links | BibTeX | Tags: Catalysis; Emulsions; Interferometry; Kinetics; Light; Microscopy; Polymerization; Scattering @article{Gruber2024872, title = {Early stages of covalent organic framework formation imaged in operando}, author = {Christoph G Gruber and Laura Frey and Roman Guntermann and Dana D Medina and Emiliano Cortés}, url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85195313423&doi=10.1038%2fs41586-024-07483-0&partnerID=40&md5=1f3ff910ff4628e063fe30f3abd6cb8e}, doi = {10.1038/s41586-024-07483-0}, issn = {00280836}, year = {2024}, date = {2024-01-01}, journal = {Nature}, volume = {630}, number = {8018}, pages = {872 – 877}, publisher = {Nature Research}, abstract = {Covalent organic frameworks (COFs) are a functional material class able to harness, convert and store energy. However, after almost 20 years of research, there are no coherent prediction rules for their synthesis conditions. This is partly because of an incomplete picture of nucleation and growth at the early stages of formation. Here we use the optical technique interferometric scattering microscopy (iSCAT)1–3 for in operando studies of COF polymerization and framework formation. We observe liquid–liquid phase separation, pointing to the existence of structured solvents in the form of surfactant-free (micro)emulsions in conventional COF synthesis. Our findings show that the role of solvents extends beyond solubility to being kinetic modulators by compartmentation of reactants and catalyst. Taking advantage of these observations, we develop a synthesis protocol for COFs using room temperature instead of elevated temperatures. This work connects framework synthesis with liquid phase diagrams and thereby enables an active design of the reaction environment, emphasizing that visualization of chemical reactions by means of light-scattering-based techniques can be a powerful approach for advancing rational materials synthesis. © The Author(s) 2024.}, note = {Cited by: 1; All Open Access, Hybrid Gold Open Access}, keywords = {Catalysis; Emulsions; Interferometry; Kinetics; Light; Microscopy; Polymerization; Scattering}, pubstate = {published}, tppubtype = {article} } Covalent organic frameworks (COFs) are a functional material class able to harness, convert and store energy. However, after almost 20 years of research, there are no coherent prediction rules for their synthesis conditions. This is partly because of an incomplete picture of nucleation and growth at the early stages of formation. Here we use the optical technique interferometric scattering microscopy (iSCAT)1–3 for in operando studies of COF polymerization and framework formation. We observe liquid–liquid phase separation, pointing to the existence of structured solvents in the form of surfactant-free (micro)emulsions in conventional COF synthesis. Our findings show that the role of solvents extends beyond solubility to being kinetic modulators by compartmentation of reactants and catalyst. Taking advantage of these observations, we develop a synthesis protocol for COFs using room temperature instead of elevated temperatures. This work connects framework synthesis with liquid phase diagrams and thereby enables an active design of the reaction environment, emphasizing that visualization of chemical reactions by means of light-scattering-based techniques can be a powerful approach for advancing rational materials synthesis. © The Author(s) 2024. |